PIK3C3 Antibody

Catalog Number:

37356

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8NEB9
NCBI Gene ID: 5289
Gene Accssion: NP_002638

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol 3-kinase, catalytic subunit type 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIK3C3 protein.

Applications:

IHC

Background:

Phosphatidylinositol 3-kinase catalytic subunit type 3?is an?enzyme?that in humans is encoded by thePIK3C3?gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF