ATG4B Antibody

Catalog Number:

37355

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y4P1
NCBI Gene ID: 23192
Gene Accssion: NP_037457

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human autophagy related 4B, cysteine peptidase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATG4B protein.

Applications:

IHC

Background:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF