ARAP1 Antibody

Catalog Number:

37347

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96P48
NCBI Gene ID: 116985
Gene Accssion: NP_001035207/Q96P48

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ARAP1 protein.

Applications:

IHC

Background:

The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF