ARHGEF6 Antibody

Catalog Number:

37342

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15052
NCBI Gene ID: 9459
Gene Accssion: NP_004831

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ARHGEF6 protein.

Applications:

IHC

Background:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF