APBA1 Antibody

Catalog Number:

37335

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q02410
NCBI Gene ID: 320
Gene Accssion: NP_001154

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human amyloid beta (A4) precursor protein-binding, family A, member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total APBA1 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF