ALDH5A1 Antibody

Catalog Number:

37324

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P51649
NCBI Gene ID: 7915
Gene Accssion: NP_001071

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human aldehyde dehydrogenase 5 family, member A1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ALDH5A1 protein.

Applications:

IHC

Background:

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF