GPT Antibody

Catalog Number:

37322

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P24298
NCBI Gene ID: 2875
Gene Accssion: NP_005300

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human glutamic-pyruvate transaminase (alanine aminotransferase)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GPT protein.

Applications:

IHC

Background:

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF