ADAMTS10 Antibody

Catalog Number:

37310

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H324
NCBI Gene ID: 81794
Gene Accssion: NP_112219

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human ADAM metallopeptidase with thrombospondin type 1 motif, 10

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADAMTS10 protein.

Applications:

IHC

Background:

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF