FZD8 Antibody

Catalog Number:

37297

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H461
NCBI Gene ID: 8325
Gene Accssion: NP_114072

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human frizzled family receptor 8

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FZD8 protein.

Applications:

IHC

Background:

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF