FAT3 Antibody

Catalog Number:

37294

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8TDW7
NCBI Gene ID: 120114
Gene Accssion: NP_001008781

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human FAT tumor suppressor homolog 3 (Drosophila)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FAT3 protein.

Applications:

IHC

Background:

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF