SSTR5 Antibody

Catalog Number:

37260

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35346
NCBI Gene ID: 6755
Gene Accssion: NP_001044.1

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human somatostatin receptor 5

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SSTR5 protein.

Applications:

WB IHC

Background:

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000

Immunohistochemistry: 1:50-1:200

Datasheet PDF