SSB Antibody

Catalog Number:

37254

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P05455
NCBI Gene ID: 6741
Gene Accssion: NP_003133.1

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Sjogren syndrome antigen B (autoantigen La)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SSB protein.

Applications:

IHC

Background:

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF