SIPA1 Antibody

Catalog Number:

37252

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96FS4
NCBI Gene ID: 6494
Gene Accssion: NP_006738.3

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human signal-induced proliferation-associated 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SIPA1 protein.

Applications:

IHC

Background:

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF