SCT Antibody

Catalog Number:

37237

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P09683
NCBI Gene ID: 6343
Gene Accssion: NP_068739.1

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human secretin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCT protein.

Applications:

IHC

Background:

Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF