SCN5A Antibody

Catalog Number:

37233

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14524
NCBI Gene ID: 6331
Gene Accssion: NP_932173

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human sodium channel, voltage-gated, type V, alpha subunit

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCN5A protein.

Applications:

IHC

Background:

The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF