SCN2A Antibody

Catalog Number:

37232

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q99250
NCBI Gene ID: 6326
Gene Accssion: NP_066287.2

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human sodium channel, voltage-gated, type II, alpha subunit

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCN2A protein.

Applications:

IHC

Background:

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF