EIF2AK2 Antibody

Catalog Number:

37220

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P19525
NCBI Gene ID: 5610
Gene Accssion: NP_002750

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Eukaryotic translation initiation factor 2-alpha kinase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EIF2AK2 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF