PKD2 Antibody

Catalog Number:

37217

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13563
NCBI Gene ID: 5311
Gene Accssion: NP_000288

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Polycystic kidney disease 2 (autosomal dominant)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PKD2 protein.

Applications:

IHC

Background:

This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF