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PRKAR1B Antibody

Catalog Number:

37215
other_names: PRKAR1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P31321
NCBI Gene ID: 5575
Gene Accssion: NP_001158230

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Protein kinase, cAMP-dependent, regulatory, type I, beta

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PRKAR1B protein.

Applications:

WB IHC

Background:

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

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