PDGFA Antibody

Catalog Number:

37213

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P04085
NCBI Gene ID: 5154
Gene Accssion: NP_002598

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Platelet-derived growth factor alpha polypeptide

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PDGFA protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF