PDCD1 Antibody

Catalog Number:

37212

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15116
NCBI Gene ID: 5133
Gene Accssion: NP_005009

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human Programmed cell death 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PDCD1 protein.

Applications:

IHC

Background:

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF