PODXL Antibody

Catalog Number:

37211

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00592
NCBI Gene ID: 5420
Gene Accssion: NP_005388

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Podocalyxin-like

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PODXL protein.

Applications:

IHC

Background:

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF