RYR1 Antibody

Catalog Number:

37887

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P21817
NCBI Gene ID: 6261
Gene Accssion: NP_000531/P21817

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human ryanodine receptor 1 (skeletal)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RYR1 protein.

Applications:

WB

Background:

This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF