PIK3CG Antibody

Catalog Number:

37827

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P48736
NCBI Gene ID: 5294
Gene Accssion: NP_002640/P48736

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIK3CG protein.

Applications:

IHC

Background:

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF