MUC16 Antibody

Catalog Number:

37173

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8WXI7
NCBI Gene ID: 94025
Gene Accssion: NP_078966

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human mucin 16, cell surface associated

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MUC16 protein.

Applications:

IHC

Background:

CA-125?(cancer?antigen?125 or carbohydrate antigen 125) also known as?mucin 16?or?MUC16?is a?protein?that in humans is encoded by the?MUC16?gene. MUC16 is a member of the mucin family glycoproteins. CA-125 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers,or other benign conditions. Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF