MUC6 Antibody

Catalog Number:

37168

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6W4X9
NCBI Gene ID: 4588
Gene Accssion: NP_005952

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mucin 6, oligomeric mucus/gel-forming

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MUC6 protein.

Applications:

IHC

Background:

The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF