CD163 Antibody

Catalog Number:

37157

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q86VB7
NCBI Gene ID: 9332
Gene Accssion: NP_004235

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CD163 molecule

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CD163 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF