ORAI1 Antibody

Catalog Number:

37133

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96D31
NCBI Gene ID: 84876
Gene Accssion: NP_116179

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human ORAI calcium release-activated calcium modulator 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ORAI1 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF