MAPK11 Antibody

Catalog Number:

37131

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15759
NCBI Gene ID: 5600
Gene Accssion: NP_002742

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase 11

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAPK11 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF