GJA8 Antibody

Catalog Number:

37121

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P48165
NCBI Gene ID: 2703
Gene Accssion: NP_005258

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human gap junction protein, alpha 8, 50kDa

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GJA8 protein.

Applications:

IHC

Background:

This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF