1-832-868-1888
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Catalog Number: |
37100 |
| other_names: | AT2; ATGR2; MRX88 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: P50052 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide corresponding to residues near the C terminal of human angiotensin II receptor, type 2 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total AGTR2 protein. |
Applications: |
IHC |
Background: |
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. |
References: |
|
appl_detail: |
Immunohistochemistry: 1:25-1:100 |
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