AGRN Antibody

Catalog Number:

37092

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00468
NCBI Gene ID: 375790
Gene Accssion: NP_940978

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human agrin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AGRN protein.

Applications:

IHC

Background:

This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF