AGPAT2 Antibody

Catalog Number:

37090

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15120
NCBI Gene ID: 10555
Gene Accssion: NP_001012745

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human 1-acylglycerol-3-phosphate O-acyltransferase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AGPAT2 protein.

Applications:

WB

Background:

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF