ADAMTS2 Antibody

Catalog Number:

37082

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95450
NCBI Gene ID: 9509
Gene Accssion: NP_055059

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human ADAM metallopeptidase with thrombospondin type 1 motif, 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADAMTS2 protein.

Applications:

IHC

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF