TNIP3 Antibody

Catalog Number:

37076

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96KP6
NCBI Gene ID: 79931
Gene Accssion: NP_079149

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human TNFAIP3 interacting protein 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNIP3 protein.

Applications:

WB

Background:

TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF