ABCC12 Antibody

Catalog Number:

37072

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96J65
NCBI Gene ID: 94160
Gene Accssion: NP_150229.2

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human ATP-binding cassette, sub-family C (CFTR/MRP), member 12

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ABCC12 protein.

Applications:

IHC

Background:

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF