SLC10A1 Antibody

Catalog Number:

37005

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14973
NCBI Gene ID: 6554
Gene Accssion: NP_003040

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human solute carrier family 10 (sodium/bile acid cotransporter family), member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC10A1 protein.

Applications:

IHC

Background:

The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF