GRIN2B Antibody

Catalog Number:

37002

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13224
NCBI Gene ID: 2904
Gene Accssion: NP_000825

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GRIN2B protein.

Applications:

WB

Background:

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.?

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF