NTSR2 Antibody

Catalog Number:

37000

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95665
NCBI Gene ID: 23620
Gene Accssion: NP_036476

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human neurotensin receptor 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NTSR2 protein.

Applications:

WB

Background:

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF