NBEA Antibody

Catalog Number:

36997

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8NFP9
NCBI Gene ID: 26960
Gene Accssion: NP_056493

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human neurobeachin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NBEA protein.

Applications:

IHC

Background:

This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF