MTNR1A Antibody

Catalog Number:

36989

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P48039
NCBI Gene ID: 4543
Gene Accssion: NP_005949

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human melatonin receptor 1A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MTNR1A protein.

Applications:

WB IHC

Background:

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100

Datasheet PDF