MUC5AC Antibody

Catalog Number:

36988

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P98088
NCBI Gene ID: 4586
Gene Accssion: XP_003119529

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mucin 5AC, oligomeric mucus/gel-forming

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MUC5AC protein.

Applications:

IHC

Background:

Mucin-5AC?is a?protein?that in humans is encoded by the?MUC5AC?gene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF