MADCAM1 Antibody

Catalog Number:

36963

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13477
NCBI Gene ID: 8174
Gene Accssion: NP_570116

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mucosal vascular addressin cell adhesion molecule 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MADCAM1 protein.

Applications:

WB

Background:

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF