LAMA3 Antibody

Catalog Number:

36945

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q16787
NCBI Gene ID: 3909
Gene Accssion: NP_000218

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human laminin, alpha 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LAMA3 protein.

Applications:

IHC

Background:

Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF