KLK2 Antibody

Catalog Number:

36940

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P20151
NCBI Gene ID: 3817
Gene Accssion: NP_005542

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human kallikrein-related peptidase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KLK2 protein.

Applications:

WB IHC

Background:

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300

Datasheet PDF