IL2RA Antibody

Catalog Number:

36931

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P01589
NCBI Gene ID: 3559
Gene Accssion: NP_000408

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human interleukin 2 receptor, alpha

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IL2RA protein.

Applications:

WB

Background:

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF