API5 Antibody

Catalog Number:

36927

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BZZ5
NCBI Gene ID: 8539
Gene Accssion: NP_006586

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human apoptosis inhibitor 5

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total API5 protein.

Applications:

WB

Background:

This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF