GCG Antibody

Catalog Number:

36900

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P01275
NCBI Gene ID: 2641
Gene Accssion: NP_002045

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human glucagon

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GCG protein.

Applications:

IHC

Background:

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF