GJB2 Antibody

Catalog Number:

36893

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P29033
NCBI Gene ID: 2706
Gene Accssion: NP_003995

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human gap junction protein, beta 2, 26kDa

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GJB2 protein.

Applications:

IHC

Background:

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF