CLDN10 Antibody

Catalog Number:

36892

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P78369
NCBI Gene ID: 9071
Gene Accssion: NP_008915

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human claudin 10

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CLDN10 protein.

Applications:

IHC

Background:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF